370nm 대역 통과 필터

Context: This patent describes a video endoscope system designed to detect colonic dysplasia (abnormal cell growth) by analyzing the natural fluorescence (autofluorescence) of tissue.

Usage of Filter: A 370nm bandpass filter (or a filter isolating the 370nm UV peak from a mercury arc lamp) is used in the illumination path. It filters the broadband light source to deliver specific ultraviolet excitation light to the tissue.

Function: To selectively excite endogenous fluorophores (such as collagen and NADH) in the colon tissue without transmitting visible light that would wash out the faint fluorescence signal.

Result: The system successfully differentiates between normal and dysplastic tissue based on the intensity and spectral characteristics of the emitted fluorescence (typically detected around 450nm), allowing for earlier cancer detection.

Context: A non-invasive diagnostic device used to measure Advanced Glycation End-products (AGEs) in a patient's skin, which serves as a biomarker for diabetes and other metabolic diseases.

Usage of Filter: The device employs a filter to isolate 370nm excitation light (UV range) from the light source before it irradiates the skin.

Function: This specific wavelength (370nm) is optimal for exciting the AGEs accumulated in the skin dermis. The filter ensures that only the excitation wavelength hits the skin, preventing overlap with the emission signal.

Result: The apparatus accurately measures the resulting autofluorescence (peaking near 440nm), providing a quantitative "skin fluorescence score" that correlates with the patient's diabetic risk or status.

Context: An imaging system capable of switching between white light reflection images and fluorescence images to identify diseased tissue.

Usage of Filter: The system utilizes a 310-370nm bandpass filter placed in the path of a high-intensity light source (like a mercury arc lamp).

Function: It blocks visible and infrared radiation while transmitting high-energy UV photons. This filtered light is coupled into a fiber optic light guide to illuminate the target tissue.

Result: This achieves a high Signal-to-Noise Ratio (SNR) for the fluorescence image, allowing the physician to visualize small lesions that are invisible under standard white light endoscopy.